As part of the ARIS J4-70159 project, our department organized a symposium titled “From Molecular Interactions to Innovative Biomedical Therapies” on October 7, 2026, under the leadership of Asst. Prof. Nina Kostevšek. The event featured outstanding speakers from the fields of cell biology, molecular interactions, molecular simulations, and the synthesis of drug delivery systems. Diverse research perspectives sharing a common goal—namely, the development of new therapies—consistently spark interesting discussions and give rise to new ideas.
# ARIS-J4-50150
# Nanostructured materials
# Jožef Stefan Institute
As part of the bilateral Slovenia–France PROTEUS project (BI-FR/25-26-PROTEUS-006) titled “Elucidation of magnetic interactions in nano-assemblies for theranostics applications,” Dr. Nina Kostevšek visited CEISAM (Centre for Education and Research on Advanced Molecular Systems) at the University of Nantes, France.
During the visit, we conducted cellular assays on our new drug delivery system based on cellular vesicles. The initial results are very promising; under the tested conditions, we observed neither cytotoxicity nor an inflammatory response.
This marks a significant step in the development of the system for future theranostic applications.
👏Kudos to the team for their excellent collaboration and successfully conducted experiments!
#PROTEUS #SloveniaFrance #bilateralproject #IJS #CEISAM #UniversityOfNantes #drugdelivery #cellularvesicles #theranostics #biomedicalresearch
Our latest article from the Nanomedicine group has been published in the Journal of Proteome Research in the scope of ARIS J4-50150 project!
🩸 In this study, we investigated whether erythrocyte membrane vesicles (EMVs) – promising biomimetic nanocarriers for drug delivery – can be produced from frozen blood while preserving their key physicochemical, structural, and protein characteristics.
Using a combination of dynamic light scattering, nano-flow cytometry, cryo-TEM, TEM, and quantitative mass-spectrometry-based proteomics, we compared EMVs prepared from fresh and −80 °C frozen blood.
✨ Key findings:
• EMVs generated from fresh and frozen blood showed broadly comparable size, surface charge, and vesicle morphology.
• Most of the proteome is largely preserved after freezing. Freezing did, however, reduce proteomic complexity and notably affected proteins such as glycophorin A and CD47, which may be important for future applications involving immune interactions and targeted drug delivery.
• Overall, the results indicate that frozen blood can be a viable and practical source for EMV production when immediate processing of fresh blood is not feasible, although further functional studies are needed.
📖 Read the full article:
https://doi.org/10.1021/acs.jproteome.6c00535
#Proteomics #ErythrocyteMembraneVesicles #Nanomedicine #DrugDelivery #BiomimeticNanoparticles #Research #Science #JozefStefanInstitute # ARIS-J4-50150
Sana Saeed from the Department for Nanostructured Materials at the Jožef
Stefan Institute received the Best Poster Award at the CAMD Summer
School 2026 – Electronic Structure Theory and Materials Design, held
from 16 to 21 August 2026.
Her poster, “Ab-initio and STM Investigation of the Nd₂Fe₁₄B Surface,”
presented a combined experimental and computational study of the (001)
surface of neodymium–iron–boron (Nd₂Fe₁₄B), an important material for
high-performance permanent magnets. Using scanning tunneling microscopy
(STM), low-energy electron diffraction (LEED), and density functional
theory (DFT) simulations, the research identified an ordered surface
reconstruction with a periodicity of 12.41 Å. The agreement between
experimental and simulated STM images supported a reconstructed Nd-rich
surface model.
The work was carried out in collaboration with researchers from the
Institute Jean Lamour in Nancy, France, and was conducted within the
framework of the GREENE project. The GREENE project focuses on advancing
research in materials and technologies relevant to sustainable energy
applications.
This award recognizes the scientific quality, relevance, and
presentation of the research and strengthens the international
visibility of materials research conducted at the Jožef Stefan
Institute.
More information about the GREENE project is available at https://www.greene-project.eu/
